To pursue a B.Sc. (Bachelor of Science) degree at Mannaniya College of Arts and Science Thiruvananthapuram, candidates must meet certain eligibility criteria. Applicants should have completed their higher secondary education (10+2) or its equivalent from a recognized board or university. They should have studied Science subjects such as Physics, Chemistry, and Biology/Mathematics as part of their curriculum. Additionally, candidates must have obtained a minimum aggregate score of 50% in their qualifying examination. The eligibility criteria may vary for different specializations within the B.Sc. program, so it is advisable for prospective students to refer to the college's official website or prospectus for specific requirements.